Two U.S. service members were killed and one remains missing after Iranian ballistic missile and drone attacks in Jordan on Friday, U.S. military officials announced. The U.S. Central Command (Centcom) confirmed the incident, stating that four other service members were medically evacuated to Jordanian hospitals but have since been released.

The attack occurs amid a period of renewed hostilities between the United States and Iran. Washington recently reimposed its blockade on Iranian ports, and Tehran declared the Strait of Hormuz closed. This escalation follows the collapse of a preliminary ceasefire agreement between the two nations less than a month after its inception.

Centcom reported that the two service members were killed in action while U.S. and partner forces defended against the Iranian assault. The military has withheld the identities of the deceased out of respect for their families, pending notification of next of kin. The Islamic Revolutionary Guard Corps (IRGC) claimed to have destroyed at least two U.S. fighter aircraft at Al-Azraq base in Jordan early Saturday, according to Iranian state media, a claim Centcom declined to elaborate on.

The U.S. death toll in the ongoing conflict has now risen to 16, with the recent declaration of death for an American Navy pilot who had been missing earlier this month. This marks the second increase in the U.S. casualty count this week.

In response to the escalating tensions, the U.S. Department of State issued a worldwide travel advisory on Saturday, urging Americans, particularly in the Middle East, to exercise increased caution. The notice highlighted the complex security environment and the potential for unforeseen escalation due to heightened tensions in the region.

Iran's Supreme Leader, Mojtaba Khamenei, stated in a written message on Saturday that the U.S. had repeatedly breached the ceasefire agreement, rendering the U.S. president's signature "utterly worthless and devoid of credibility." Khamenei accused the U.S. of seeking to escalate the conflict and warned of "unforgettable lessons" for America.

Jordan's military had previously reported intercepting 10 Iranian missiles fired into its airspace overnight Friday, confirming no damage from the incident. The preliminary ceasefire deal, struck in June, began to unravel in early July, with U.S. President Trump declaring the agreement over on July 8.

U.S. Defense Secretary Pete Hegseth reacted to the news of the service members' deaths, writing on X (formerly Twitter) that their sacrifice "only stiffens our resolve."